Title : Pivotal effects of phosphodiesterase inhibitors on myocyte contractility and viability in normal and ischemic hearts.

Pub. Date : 2009 Jan

PMID : 19060915






1 Functional Relationships(s)
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1 The PDE type-3, -4, and -5 (PDE3, PDE4, PDE5) are localized to specific regions of the cardiomyocyte, such as the sarcoplasmic reticulum and Z-disc, where they are likely to influence cAMP/cGMP signaling to the end effectors of contractility. Cyclic AMP phosphodiesterase 5A Homo sapiens