Title : Clinical utility of genotyping the 677C>T variant of methylenetetrahydrofolate reductase in humans is decreased in the post-folic acid fortification era.

Pub. Date : 2009 Jan

PMID : 19056652






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Major factors affecting plasma total homocysteine (tHcy) concentrations include folate concentrations and polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene. thcy methylenetetrahydrofolate reductase Homo sapiens
2 Major factors affecting plasma total homocysteine (tHcy) concentrations include folate concentrations and polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene. thcy methylenetetrahydrofolate reductase Homo sapiens
3 MTHFR 677TT homozygotes had higher (P < 0.01) tHcy concentrations both before and after fortification compared with MTHFR 677CC homozygotes. thcy methylenetetrahydrofolate reductase Homo sapiens