Title : Nicotine suppresses bone sialoprotein gene expression.

Pub. Date : 2009 Oct

PMID : 19054295






1 Functional Relationships(s)
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1 Nicotine decreased the nuclear protein binding to the cAMP response element (CRE), fibroblast growth factor 2 response element (FRE) and homeodomain protein-binding site (HOX) at 12 and 24 h. CONCLUSION: This study indicates that nicotine suppresses BSP transcription mediated through CRE, FRE and HOX elements in the proximal promoter of the rat BSP gene. Nicotine fibroblast growth factor 2 Rattus norvegicus