Title : Polyhalogenated dibenzo-p-dioxins and dibenzofurans and the immune system. 2. In vitro effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on lymphocytes of venous blood from man and a non-human primate (Callithrix jacchus).

Pub. Date : 1991

PMID : 1905127






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 However, incubation with TCDD in the culture medium together with the mitogen led to a pronounced decrease in the percentage of the lymphocyte subset with the surface marker CD4, and a concomitant increase in the percentage of CD8+ cells. Polychlorinated Dibenzodioxins CD4 molecule Homo sapiens
2 A closer analysis of the T lymphocyte subsets affected revealed the CD4+ CDw29+ (helper-inducer cells) to be the main target for the action of TCDD. Polychlorinated Dibenzodioxins CD4 molecule Homo sapiens