Title : Determination of the inhibitory potential of 6 fluoroquinolones on CYP1A2 and CYP2C9 in human liver microsomes.

Pub. Date : 2008 Dec

PMID : 19026171






1 Functional Relationships(s)
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1 METHODS: Probe substrates, phenacetin (CYP1A2), and tolbutamide (CYP2C9) were incubated with human liver microsomes and the metabolites were analyzed by liquid chromatography/mass spectrometry using electrospray ionization in positive or negative mode. Tolbutamide cytochrome P450 family 2 subfamily C member 9 Homo sapiens