Title : Mineralocorticoid receptors: emerging complexity and functional diversity.

Pub. Date : 2009 Feb

PMID : 19022273






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 11beta-hydroxysteroid dehydrogenase type 2 (11beta-HSD2) is believed to confer specificity on aldosterone to activate MR by inactivating 11beta-hydroxyglucocorticoids (corticosterone, cortisol) that are 100-1000 times more abundant in plasma than aldosterone and that can also bind and activate MR. Corticosterone hydroxysteroid 11-beta dehydrogenase 2 Homo sapiens