Title : Perturbation of the lipid phase of a membrane is not involved in the modulation of MRP1 transport activity by flavonoids.

Pub. Date : 2009

PMID : 19020811






1 Functional Relationships(s)
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1 Since the activity of the other MDR transporter, P-glycoprotein, is sensitive to membrane perturbation, we aimed to check whether the changes in lipid bilayer properties induced by flavones (apigenin, acacetin) and flavonols (morin, myricetin) were related to their MRP1 inhibitory activity. myricetin ATP binding cassette subfamily B member 1 Homo sapiens