Title : Identification of mitochondrial F(1)F(0)-ATP synthase interacting with galectin-3 in colon cancer cells.

Pub. Date : 2008 Oct

PMID : 19016746






3 Functional Relationships(s)
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1 Suppression of galectin-3 resulted in G0/G1 progression of human colon cancer cells arrested at S, S/G2 and G2/M phase in the presence of doxorubicin, and etoposide or nocodazole, respectively. Nocodazole galectin 3 Homo sapiens
2 Compared to cells in which ATP synthase d-subunit was suppressed alone, sub-G1 fraction caused by etoposide or nocodazole was decreased in cells with galectin-3 suppression alone. Nocodazole galectin 3 Homo sapiens
3 In the presence of cell cycle synchronizing drugs, doxorubicin, etoposide, or nocodazole, suppression of galectin-3 induced cell cycle progression to G0/G1 phase. Nocodazole galectin 3 Homo sapiens