Protein Name galectin 3
Organism Homo sapiens
Gene ID 3958
Gene Symbol


UniProt P17931 (LEG3_HUMAN), A0A024R693 (A0A024R693_HUMAN)
Relationships Total Number of functionally related compound(s) : 656
Total Number of Articles : 907

galectin 3

Gene Summary

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014]

  • galectin-3
  • 35 kDa lectin
  • IgE-binding protein
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