| Protein Name | galectin 3 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 3958 |
| Gene Symbol | LGALS3 |
| UniProt | P17931 (LEG3_HUMAN), A0A024R693 (A0A024R693_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
656
Total Number of Articles : 907 |
Description |
galectin 3 |
| Gene Summary |
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014] |
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| Properties | |