Title : In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway.

Pub. Date : 2008 Dec

PMID : 19002586






1 Functional Relationships(s)
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1 Tumors from capsaicin treated mice demonstrated increased apoptosis, which was related to the activation of JNK and increased cytosolic protein expression of Bax, cytochrome c, AIF and cleaved caspase-3, as compared with controls. Capsaicin BCL2-associated X protein Mus musculus