Title : Tyrosinases from two different loci are expressed by normal and by transformed melanocytes.

Pub. Date : 1991 Jan 15

PMID : 1898730






1 Functional Relationships(s)
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1 By use of immune affinity purification protocols, we have isolated the proteins encoded by the brown and albino loci and have determined that both have the catalytic functions ascribed to tyrosinase, i.e. hydroxylation of tyrosine to 3,4-dihydroxyphenylalanine (DOPA) and the oxidation of DOPA to DOPAquinone. Tyrosine tyrosinase Mus musculus