Title : Leptin stimulates the proliferation of human oesophageal adenocarcinoma cells via HB-EGF and Tgfalpha mediated transactivation of the epidermal growth factor receptor.

Pub. Date : 2008

PMID : 18986098






1 Functional Relationships(s)
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1 Leptin stimulated proliferation in four OAC lines expressing leptin receptors (OE33, OE19, BIC-1 and FLO) and this was abolished by specific EGFR inhibitors (PD153035 and AG1478). 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline epidermal growth factor receptor Homo sapiens