Pub. Date : 2008
PMID : 18979154
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The flavonoid quercetin induces apoptosis and inhibits migration through a MAPK-dependent mechanism in osteoblasts. | Quercetin | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | Western blot analysis showed that quercetin induced activation of ERK and p38, but not JNK. | Quercetin | mitogen-activated protein kinase 1 | Homo sapiens |
| 3 | Quercetin-induced cell death was prevented by the ERK inhibitor PD98059, but not by inhibitors of p38 and JNK. | Quercetin | mitogen-activated protein kinase 1 | Homo sapiens |
| 4 | Quercetin inhibited cell migration, and its effect was prevented by inhibitors of ERK and p38. | Quercetin | mitogen-activated protein kinase 1 | Homo sapiens |
| 5 | Taken together, these findings suggest that quercetin induces apoptosis through a mitochondria-dependent mechanism involving ERK activation and inhibits migration through activation of ERK and p38 pathways. | Quercetin | mitogen-activated protein kinase 1 | Homo sapiens |
| 6 | Taken together, these findings suggest that quercetin induces apoptosis through a mitochondria-dependent mechanism involving ERK activation and inhibits migration through activation of ERK and p38 pathways. | Quercetin | mitogen-activated protein kinase 1 | Homo sapiens |