Title : Intrathecal Raf-1-selective siRNA attenuates sustained morphine-mediated thermal hyperalgesia.

Pub. Date : 2008 Dec 28

PMID : 18976650






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Enhanced excitatory pain neurotransmitter (such as calcitonin gene-related peptide (CGRP)) release in the dorsal horn of the spinal cord may play a role in sustained morphine-mediated paradoxical pain. Morphine calcitonin-related polypeptide alpha Rattus norvegicus
2 Enhanced excitatory pain neurotransmitter (such as calcitonin gene-related peptide (CGRP)) release in the dorsal horn of the spinal cord may play a role in sustained morphine-mediated paradoxical pain. Morphine calcitonin-related polypeptide alpha Rattus norvegicus
3 Recently we have demonstrated that inhibition of Raf-1 attenuates sustained morphine treatment-mediated augmentation of CGRP release in vitro, in cultured primary sensory neurons. Morphine calcitonin-related polypeptide alpha Rattus norvegicus