Pub. Date : 2008 Nov 1
PMID : 18974147
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Imatinib mesylate induces quiescence in gastrointestinal stromal tumor cells through the CDH1-SKP2-p27Kip1 signaling axis. | Imatinib Mesylate | cyclin dependent kinase inhibitor 1B | Homo sapiens |
| 2 | We report here that imatinib stimulates cellular quiescence in a proportion of GIST cells as evidenced by up-regulation of the CDK inhibitor p27(Kip1), loss of cyclin A, and reduced BrdUrd incorporation. | Imatinib Mesylate | cyclin dependent kinase inhibitor 1B | Homo sapiens |