Title : Mechanical loading highly increases IL-6 production and decreases OPG expression by osteoblasts.

Pub. Date : 2009 Apr

PMID : 18974013






1 Functional Relationships(s)
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1 IL-6 neutralizing antibodies and piroxicam inhibited the decrease OPG expression, but did not modify RANKL mRNA level, indicating that IL-6 and PGE(2) induce a decrease of the OPG/RANKL ratio. Piroxicam interleukin 6 Mus musculus