Title : Drug interaction potential of 2-((3,4-dichlorophenethyl)(propyl)amino)-1-(pyridin-3-yl)ethanol (LK-935), the novel nonstatin-type cholesterol-lowering agent.

Pub. Date : 2009 Feb

PMID : 18971317






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Activation of hCAR and hPXR by atorvastatin and the subsequent induction of not only CYP2B6 and CYP3A4 but also of CYP2C9 present an additional target by which atorvastatin, a widely used cholesterol-lowering drug, can modify the kinetics of numerous drugs. Cholesterol cytochrome P450 family 2 subfamily C member 9 Homo sapiens