Pub. Date : 2009 May
PMID : 18953480
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | METHODS AND RESULTS: Guggulsterone inhibited TNF-alpha-induced endothelial TF protein expression and surface activity in a concentration-dependent manner; in contrast, dexamethasone did not affect TNF-alpha-induced TF expression. | pregna-4,17-diene-3,16-dione | tumor necrosis factor | Mus musculus |
| 2 | Real-time polymerase chain reaction revealed that guggulsterone inhibited TNF-alpha-induced TF mRNA expression; moreover, it impaired activation of the MAP kinases JNK and p38, while that of ERK remained unaffected. | pregna-4,17-diene-3,16-dione | tumor necrosis factor | Mus musculus |