Title : Galantamine-induced improvements in cognitive function are not related to alterations in alpha(4)beta (2) nicotinic receptors in early Alzheimer's disease as measured in vivo by 2-[18F]fluoro-A-85380 PET.

Pub. Date : 2009 Jan

PMID : 18949462






1 Functional Relationships(s)
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1 Cholinesterase inhibitors (i.e., galantamine) that potentiate cholinergic neurotransmission improve cognitive function in Alzheimer"s disease (AD); however, the relationship between these effects and associated changes in nAChRs are yet to be established in vivo. Galantamine butyrylcholinesterase Homo sapiens