Title : The role of interleukin-1beta in murine cigarette smoke-induced emphysema and small airway remodeling.

Pub. Date : 2009 Apr

PMID : 18931327






2 Functional Relationships(s)
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1 In C57Bl/6 mice, acute smoke-mediated increases in inflammatory cells, serum IL-1beta, and serum TNF-alpha were blocked by z-VAD-fmk, a pan-caspase inhibitor, or z-WEHD-fmk, a caspase-1 (IL-1-converting enzyme, [ICE]) inhibitor. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone caspase 1 Mus musculus
2 In C57Bl/6 mice, acute smoke-mediated increases in inflammatory cells, serum IL-1beta, and serum TNF-alpha were blocked by z-VAD-fmk, a pan-caspase inhibitor, or z-WEHD-fmk, a caspase-1 (IL-1-converting enzyme, [ICE]) inhibitor. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone caspase 1 Mus musculus