Title : Glycine regulates the production of pro-inflammatory cytokines in lean and monosodium glutamate-obese mice.

Pub. Date : 2008 Dec 3

PMID : 18930730






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 To determine the role of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) in the modulation of this inflammatory response evoked by glycine, we examined its expression levels in fat tissue. Glycine peroxisome proliferator activated receptor gamma Mus musculus
2 To determine the role of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) in the modulation of this inflammatory response evoked by glycine, we examined its expression levels in fat tissue. Glycine peroxisome proliferator activated receptor gamma Mus musculus
3 Glycine clearly increased PPAR-gamma expression in lean mice but not in MSG/Ob mice. Glycine peroxisome proliferator activated receptor gamma Mus musculus
4 In conclusion, our findings suggest that glycine suppresses the pro-inflammatory cytokines production and increases adiponectin secretion in vivo through the activation of PPAR-gamma. Glycine peroxisome proliferator activated receptor gamma Mus musculus