Pub. Date : 2009 Feb
PMID : 18922879
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In the present study, structurally diverse coenzyme-substrate derivatives mimicking this type for pyridoxal 5"-phosphate-dependent human ornithine decarboxylase (hODC), a potential anticancer target, were designed, synthesized, and tested to elucidate the structural requirements for optimal inhibition of intracellular ODC as well as of tumor cell proliferation. | Pyridoxal Phosphate | ornithine decarboxylase 1 | Homo sapiens |
2 | In the present study, structurally diverse coenzyme-substrate derivatives mimicking this type for pyridoxal 5"-phosphate-dependent human ornithine decarboxylase (hODC), a potential anticancer target, were designed, synthesized, and tested to elucidate the structural requirements for optimal inhibition of intracellular ODC as well as of tumor cell proliferation. | Pyridoxal Phosphate | ornithine decarboxylase 1 | Homo sapiens |
3 | In the present study, structurally diverse coenzyme-substrate derivatives mimicking this type for pyridoxal 5"-phosphate-dependent human ornithine decarboxylase (hODC), a potential anticancer target, were designed, synthesized, and tested to elucidate the structural requirements for optimal inhibition of intracellular ODC as well as of tumor cell proliferation. | Pyridoxal Phosphate | ornithine decarboxylase 1 | Homo sapiens |