Title : Accelerated dephosphorylation of the beta2-adrenergic receptor by mutation of the C-terminal lysines: effects on ubiquitination, intracellular trafficking, and degradation.

Pub. Date : 2008 Nov 11

PMID : 18841999






2 Functional Relationships(s)
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1 To explore the roles of the two post-translational modifications, we mutated the three C-terminal lysines to arginines in the human beta 2-adrenergic receptor (beta 2AR) (K348/372/375R). Arginine adrenoceptor beta 2 Homo sapiens
2 To explore the roles of the two post-translational modifications, we mutated the three C-terminal lysines to arginines in the human beta 2-adrenergic receptor (beta 2AR) (K348/372/375R). Arginine adrenoceptor beta 2 Homo sapiens