Pub. Date : 2008 Oct
PMID : 18836460
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Glutaminyl cyclase inhibition attenuates pyroglutamate Abeta and Alzheimer"s disease-like pathology. | Pyrrolidonecarboxylic Acid | amyloid beta (A4) precursor protein | Mus musculus |
| 2 | Because of their abundance, resistance to proteolysis, rapid aggregation and neurotoxicity, N-terminally truncated and, in particular, pyroglutamate (pE)-modified Abeta peptides have been suggested as being important in the initiation of pathological cascades resulting in the development of Alzheimer"s disease. | Pyrrolidonecarboxylic Acid | amyloid beta (A4) precursor protein | Mus musculus |
| 3 | Because of their abundance, resistance to proteolysis, rapid aggregation and neurotoxicity, N-terminally truncated and, in particular, pyroglutamate (pE)-modified Abeta peptides have been suggested as being important in the initiation of pathological cascades resulting in the development of Alzheimer"s disease. | Pyrrolidonecarboxylic Acid | amyloid beta (A4) precursor protein | Mus musculus |