Title : Inhibition of T24 human bladder carcinoma cell migration by RNA interference suppressing the expression of HD-PTP.

Pub. Date : 2009 Jan 8

PMID : 18835089






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 We found that, in Epidermal Growth Factor (EGF) stimulated cells, Src binds to and phosphorylates HD-PTP on tyrosine residues. Tyrosine epidermal growth factor Homo sapiens
2 We found that, in Epidermal Growth Factor (EGF) stimulated cells, Src binds to and phosphorylates HD-PTP on tyrosine residues. Tyrosine epidermal growth factor Homo sapiens
3 Following stimulation with EGF, HD-PTP is tyrosine-phosphorylated and releases FAK which will ultimately contribute to the turn-over of focal adhesion and, therefore, to cell motility. Tyrosine epidermal growth factor Homo sapiens