Title : Low-dose dexamethasone-supplemented fluid resuscitation reverses endotoxin-induced acute renal failure and prevents cortical microvascular hypoxia.

Pub. Date : 2009 May

PMID : 18827749






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The main production of NO under septic conditions derives from iNOS, an enzyme that can be blocked by dexamethasone (DEX). Dexamethasone nitric oxide synthase 2 Rattus norvegicus
2 The main production of NO under septic conditions derives from iNOS, an enzyme that can be blocked by dexamethasone (DEX). Dexamethasone nitric oxide synthase 2 Rattus norvegicus
3 In an animal model of endotoxin-induced renal failure, we tested the hypothesis that inhibition of iNOS by low-dose DEX would improve an impaired intrarenal oxygenation and kidney function. Dexamethasone nitric oxide synthase 2 Rattus norvegicus