Title : PCNA damage caused by antineoplastic drugs.

Pub. Date : 2008 Dec 15

PMID : 18823950






2 Functional Relationships(s)
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1 Structurally diverse chemotherapeutic and chemopreventive drugs, including camptothecin, doxorubicin, sanguinarine, and others, were found to cause covalent crosslinking of proliferating cell nuclear antigen (PCNA) trimers in mammalian cells exposed to fluorescent light. sanguinarine proliferating cell nuclear antigen Homo sapiens
2 Structurally diverse chemotherapeutic and chemopreventive drugs, including camptothecin, doxorubicin, sanguinarine, and others, were found to cause covalent crosslinking of proliferating cell nuclear antigen (PCNA) trimers in mammalian cells exposed to fluorescent light. sanguinarine proliferating cell nuclear antigen Homo sapiens