Pub. Date : 1991 Sep 1
PMID : 1881896
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In neonatal neuron cultures, competition of 125I-AII specific binding with the above ligands revealed a potency series of CGP42112A = AII greater than [Phe(p- NH2)6]AII greater than PD123177 much greater than DuP753. | PD 123177 | angiotensinogen | Rattus norvegicus |
2 | 125I-AII specific binding to neonate neuronal cultures was reduced 73-84% by 1 microM PD123177, and the residual 125I-AII specific binding was eliminated by DuP753. | PD 123177 | angiotensinogen | Rattus norvegicus |
3 | Also, in neuron cultures, AII induced decreases in basal cGMP that were completely blocked by PD123177 or CGP42112A but not by DuP753. | PD 123177 | angiotensinogen | Rattus norvegicus |