Title : Effects of dasatinib on EphA2 receptor tyrosine kinase activity and downstream signalling in pancreatic cancer.

Pub. Date : 2008 Oct 7

PMID : 18797457






1 Functional Relationships(s)
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1 Dasatinib also inhibited ligand-induced binding of EphA2 to the ubiquitin ligase Cbl, and the internalisation and degradation of EphA2, suggesting that these processes are dependent on kinase activity. Dasatinib Cbl proto-oncogene Homo sapiens