Title : Novel opportunities for thymidylate metabolism as a therapeutic target.

Pub. Date : 2008 Sep

PMID : 18790783






1 Functional Relationships(s)
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1 In this article, we present further evidence showing that elevated expression of dUTPase can protect breast cancer cells from the expansion of the intracellular uracil pool, translating to reduced growth inhibition following treatment with 5-FU. Uracil Deoxyuridine triphosphatase Drosophila melanogaster