Title : Confirmation that cytochrome P450 2C8 (CYP2C8) plays a minor role in (S)-(+)- and (R)-(-)-ibuprofen hydroxylation in vitro.

Pub. Date : 2008 Dec

PMID : 18787056






1 Functional Relationships(s)
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1 In contrast, less inhibition was observed with montelukast (CYP2C8 inhibitor, < or =35%) and anti-CYP2C8 mAbs (< or =24%) at all concentrations of IBU. montelukast cytochrome P450 family 2 subfamily C member 8 Homo sapiens