Title : Flesinoxan challenge suggests that chronic treatment with paroxetine in rats does not desensitize receptors controlling 5-HT synthesis.

Pub. Date : 2008 Dec

PMID : 18786747






2 Functional Relationships(s)
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1 5-HT(1A) receptor sensitivity following chronic administration of the SSRI paroxetine was assessed by the ability of an acute challenge with the 5-HT(1A) agonist, flesinoxan, to modulate 5-HT synthesis in the rat brain. flesinoxan 5-hydroxytryptamine receptor 1A Rattus norvegicus
2 5-HT(1A) receptor sensitivity following chronic administration of the SSRI paroxetine was assessed by the ability of an acute challenge with the 5-HT(1A) agonist, flesinoxan, to modulate 5-HT synthesis in the rat brain. flesinoxan 5-hydroxytryptamine receptor 1A Rattus norvegicus