Title : BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis?

Pub. Date : 2008 Sep 9

PMID : 18782444






1 Functional Relationships(s)
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1 Further, we show that BRAF mutations occur in association with CIMP phenotype in colorectal serrated polyps and verified that colorectal serrated polyps and MSI CRC show a similar frequency of BRAF mutations. Cyclic IMP B-Raf proto-oncogene, serine/threonine kinase Homo sapiens