Title : Nicotine relieves anxiogenic-like behavior in mice that overexpress the read-through variant of acetylcholinesterase but not in wild-type mice.

Pub. Date : 2008 Dec

PMID : 18776044






2 Functional Relationships(s)
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1 Nicotine relieves anxiogenic-like behavior in mice that overexpress the read-through variant of acetylcholinesterase but not in wild-type mice. Nicotine acetylcholinesterase Mus musculus
2 In summary, we found that nicotine acts as an anxiolytic in TgR mice but not in control mice and that continuously overexpressed AChE-R regulates striatal gene expression, modulating cholinergic signaling and stress-related pathways. Nicotine acetylcholinesterase Mus musculus