Protein Name acetylcholinesterase
Organism Mus musculus
Gene ID 11423
Gene Symbol

Ache

UniProt P21836 (ACES_MOUSE), Q543Z1 (Q543Z1_MOUSE)
Relationships Total Number of functionally related compound(s) : 879
Total Number of Articles : 1088
Description

acetylcholinesterase

Gene Summary

Enables acetylcholinesterase activity; identical protein binding activity; and laminin binding activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including acetylcholine catabolic process; acetylcholine receptor signaling pathway; and regulation of receptor recycling. Located in several cellular components, including basement membrane; cell surface; and neuromuscular junction. Is expressed in several structures, including alimentary system; genitourinary system; musculature; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease; drug dependence (multiple); epilepsy; myasthenia gravis; and subacute delirium. Orthologous to human ACHE (acetylcholinesterase (Yt blood group)). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • acetylcholinesterase
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Properties