Protein Name acetylcholinesterase
Organism Mus musculus
Gene ID 11423
Gene Symbol


UniProt P21836 (ACES_MOUSE), Q543Z1 (Q543Z1_MOUSE)
Relationships Total Number of functionally related compound(s) : 879
Total Number of Articles : 1088


Gene Summary

Enables several functions, including acetylcholinesterase activity; identical protein binding activity; and protein self-association. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including acetylcholine catabolic process; acetylcholine receptor signaling pathway; and regulation of receptor recycling. Located in several cellular components, including basement membrane; cell surface; and neuromuscular junction. Is expressed in several structures, including alimentary system; genitourinary system; musculature; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease; epilepsy; and myasthenia gravis. Orthologous to human ACHE (acetylcholinesterase (Cartwright blood group)). [provided by Alliance of Genome Resources, Apr 2022]

  • acetylcholinesterase
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