Pub. Date : 2008 Nov
PMID : 18771527
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Overexpression of carboxylesterase-2 results in enhanced efficacy of topoisomerase I inhibitor, irinotecan (CPT-11), for multiple myeloma. | Irinotecan | carboxylesterase 2 | Homo sapiens |
| 2 | Overexpression of carboxylesterase-2 results in enhanced efficacy of topoisomerase I inhibitor, irinotecan (CPT-11), for multiple myeloma. | Irinotecan | carboxylesterase 2 | Homo sapiens |
| 3 | Interestingly, high expression of hCE-2 represented the nature of normal plasma cells, suggesting that hCE-2 could efficiently generate SN-38 within the plasma cells. | Irinotecan | carboxylesterase 2 | Homo sapiens |
| 4 | Interestingly, high expression of hCE-2 represented the nature of normal plasma cells, suggesting that hCE-2 could efficiently generate SN-38 within the plasma cells. | Irinotecan | carboxylesterase 2 | Homo sapiens |
| 5 | As expected, higher sensitivity to CPT-11 was observed in hCE-2-overexpressing U266 cells than mock U266 cells. | Irinotecan | carboxylesterase 2 | Homo sapiens |