Pub. Date : 2008 Oct 8
PMID : 18767864
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | B16-F1 cells treated with MACs at various concentrations showed reduced extracellular matrix (ECM) proteinases including matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) by gelatin zymography assay. | macs | matrix metallopeptidase 9 | Mus musculus |
2 | B16-F1 cells treated with MACs at various concentrations showed reduced extracellular matrix (ECM) proteinases including matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) by gelatin zymography assay. | macs | matrix metallopeptidase 9 | Mus musculus |
3 | Therefore, it was suggested that MACs could mediate B16-F1 cell metastasis by reduction of MMP-2 and MMP-9 activities involving the suppression of the Ras/PI3K signaling pathway. | macs | matrix metallopeptidase 9 | Mus musculus |