Title : Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation.

Pub. Date : 2008 Sep 1

PMID : 18765530






1 Functional Relationships(s)
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1 However, 24 h after exposure, sorafenib- and vorinostat-treated cells exhibited markedly diminished expression of c-FLIP-s, full-length BID, BCL-2, BCL-XL, MCL-1, XIAP, increased expression of BIM, and increased activation of BAX, BAK, and BAD. Sorafenib X-linked inhibitor of apoptosis Homo sapiens