Title : Genistein induces cell apoptosis in MDA-MB-231 breast cancer cells via the mitogen-activated protein kinase pathway.

Pub. Date : 2008 Oct

PMID : 18761399






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Genistein down-regulates Bcl-2 and up-regulates Bax. Genistein BCL2 apoptosis regulator Homo sapiens
2 NF-kappaB binding sites are present in the promoter of Bcl-2, suggesting that genistein might inhibit the expression of Bcl-2 through down-regulation of NF-kappaB. Genistein BCL2 apoptosis regulator Homo sapiens
3 NF-kappaB binding sites are present in the promoter of Bcl-2, suggesting that genistein might inhibit the expression of Bcl-2 through down-regulation of NF-kappaB. Genistein BCL2 apoptosis regulator Homo sapiens