Title : Hypoxanthine-maintained two-cell block in mouse embryos: dependence on glucose and effect of hypoxanthine phosphoribosyltransferase inhibitors.

Pub. Date : 1991 Jun

PMID : 1873380






2 Functional Relationships(s)
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1 Hypoxanthine-maintained two-cell block in mouse embryos: dependence on glucose and effect of hypoxanthine phosphoribosyltransferase inhibitors. Hypoxanthine hypoxanthine guanine phosphoribosyl transferase Mus musculus
2 Assays of hypoxanthine phosphoribosyltransferase (HPRT) activity in lysates of four-cell embryos determined that the drugs 6-mercapto-9-(tetrahydro-2-furyl)-purine (MPTF) and 6-mercaptopurine (6-MP), but not 6-azauridine (6-AzaU), prevented salvage of hypoxanthine. Hypoxanthine hypoxanthine guanine phosphoribosyl transferase Mus musculus