Protein Name hypoxanthine phosphoribosyltransferase 1
Organism Mus musculus
Gene ID 15452
Gene Symbol

Hprt1

UniProt P00493 (HPRT_MOUSE)
Relationships Total Number of functionally related compound(s) : 178
Total Number of Articles : 207
Description

hypoxanthine phosphoribosyltransferase 1

Gene Summary

The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. [provided by RefSeq, Sep 2015]

synonyms
  • hypoxanthine-guanine phosphoribosyltransferase
  • HGPRT
  • HGPRTase
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Properties