Title : Glucose-6-phosphate dehydrogenase: a novel therapeutic target in cardiovascular diseases.

Pub. Date : 2008 Sep

PMID : 18729006






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 While it is understood that G6PD-derived NADPH, which is a cofactor for NADPH oxidase, enhances superoxide anion generation and elevates oxidative stress in diabetes, heart failure, and angiotensin II-induced hypertrophy of smooth muscle, there are no specific drugs available to study the role of G6PD and G6PD-derived NADPH in organ function and the development of human diseases. Superoxides glucose-6-phosphate dehydrogenase Homo sapiens