Title : Tumor-growth-promoting cyclooxygenase-2 prostaglandin E2 pathway provides medulloblastoma therapeutic targets.

Pub. Date : 2008 Oct

PMID : 18715952






1 Functional Relationships(s)
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1 PGE(2) is synthesized from arachidonic acid by cyclooxygenases (COX) and prostaglandin E synthases (PGES) and mediates its biological activity through binding to the four prostanoid receptors EP(1) through EP(4). Arachidonic Acid prostaglandin E synthase Homo sapiens