Title : [Variations in glycoprotein IIb-IIIa (alphaIIb/beta3-integrin) content in healthy donors. Influence on platelet aggregation activity and efficacy of aspirin action].

Pub. Date : 2008 May-Jun

PMID : 18712091






2 Functional Relationships(s)
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1 The level and rate of platelet aggregation induced by ADP (1.25-20 M) correlated with GP IIb-IIIa number (r from 0.315 to 0.591) and were higher in a group of donors with high in comparison with low GP IIb-IIIa content (> 60 and (40-50) x 10(3) per platelet respectively). Adenosine Diphosphate integrin subunit alpha 2b Homo sapiens
2 The level and rate of platelet aggregation induced by ADP (1.25-20 M) correlated with GP IIb-IIIa number (r from 0.315 to 0.591) and were higher in a group of donors with high in comparison with low GP IIb-IIIa content (> 60 and (40-50) x 10(3) per platelet respectively). Adenosine Diphosphate integrin subunit alpha 2b Homo sapiens