Title : Effects of CYP3A5 and MDR1 single nucleotide polymorphisms on drug interactions between tacrolimus and fluconazole in renal allograft recipients.

Pub. Date : 2008 Oct

PMID : 18704002






1 Functional Relationships(s)
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1 The aim of this study was to examine the influence of the CYP3A4, CYP3A5, and MDR1 single nucleotide polymorphisms on changes in tacrolimus exposure and dosing in renal allograft recipients treated with fluconazole. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens