Title : The combination of epidermal growth factor receptor inhibitors with gemcitabine and radiation in pancreatic cancer.

Pub. Date : 2008 Aug 15

PMID : 18698032






2 Functional Relationships(s)
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1 RESULTS: We found in vitro that gemcitabine induced phosphorylation of EGFR at Y845 and Y1173 that was blocked by erlotinib. gemcitabine epidermal growth factor receptor Homo sapiens
2 CONCLUSIONS: These results show that the EGFR inhibitors cetuximab and erlotinib increase the efficacy of gemcitabine-radiation. gemcitabine epidermal growth factor receptor Homo sapiens