Title : Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice.

Pub. Date : 2008 Aug

PMID : 18666257

1 Functional Relationships(s)
Compound Name
Protein Name
1 Reactive oxygen species (ROS) accumulation in liver increases hepatic production of transforming growth factor (TGF)-beta1 at all stages of NASH; adiponectin/AdipoR2 signaling ameliorated TGF-beta-induced ROS accumulation in primary cultured hepatocytes, by enhancing PPAR-alpha activity and catalase expression. Reactive Oxygen Species peroxisome proliferator activated receptor alpha Mus musculus