Title : Prostate specific antigen gene expression in androgen insensitive prostate carcinoma subculture cell line.

Pub. Date : 2008 Jul-Aug

PMID : 18649734






2 Functional Relationships(s)
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1 When the PC-J cells were cotransfected with androgen receptor, androgen receptor coactivators and PSA reporter vector cells, the reporter assays indicated that nuclear receptor coactivator 4 (NCOA4) but not androgen receptor activator 24 (ARA24) increased the sensitivity and maximum stimulation of dihydrotestosterone (DHT)-inducing PSA promoter activity. Dihydrotestosterone nuclear receptor coactivator 4 Homo sapiens
2 When the PC-J cells were cotransfected with androgen receptor, androgen receptor coactivators and PSA reporter vector cells, the reporter assays indicated that nuclear receptor coactivator 4 (NCOA4) but not androgen receptor activator 24 (ARA24) increased the sensitivity and maximum stimulation of dihydrotestosterone (DHT)-inducing PSA promoter activity. Dihydrotestosterone nuclear receptor coactivator 4 Homo sapiens