Protein Name nuclear receptor coactivator 4
Organism Homo sapiens
Gene ID 8031
Gene Symbol

NCOA4

UniProt Q13772 (NCOA4_HUMAN), A0A024QZI5 (A0A024QZI5_HUMAN), B2R5V0 (B2R5V0_HUMAN), Q96E88 (Q96E88_HUMAN)
Relationships Total Number of functionally related compound(s) : 81
Total Number of Articles : 90
Description

nuclear receptor coactivator 4

Gene Summary

This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14. [provided by RefSeq, Feb 2009]

synonyms
  • nuclear receptor coactivator 4
  • 70 kDa AR-activator
  • 70 kDa androgen receptor coactivator
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Properties