Title : Antiproliferative effect of sulindac in colonic neoplasia prevention: role of COOH-terminal Src kinase.

Pub. Date : 2008 Jul

PMID : 18644992






1 Functional Relationships(s)
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1 Sulindac-mediated Csk induction was replicated in the human colorectal cancer cell line HT-29, with a corresponding suppression of both Src kinase activity (63% of vehicle; P < 0.05) and E-cadherin tyrosine phosphorylation (an in vivo Src target). Tyrosine C-terminal Src kinase Homo sapiens